The Blackhawks tweeted that Campbell is "not done with the Hawks! Soupy will join the front office, assisting with marketing, community and youth hockey initiatives."
"I'm excited to transition into the next step in both my professional career and life," Campbell said in a statement. "I'm grateful to the countless number of teammates, coaches, team staff and fans that I have crossed paths with throughout my playing career in Chicago, Buffalo, Florida and San Jose. The Blackhawks organization has allowed me to take on this challenge and I'm thankful for this new opportunity."
He finishes his career with 87 goals, 417 assists and was a plus-63.
Campbell spent his first six-plus seasons in Buffalo, establishing himself as an All-Star. He was traded to San Jose at the deadline in 2008 and then signed as a free agent with Chicago that offseason, becoming one of the building blocks around young stars Jonathan Toews and Patrick Kane.
The 2010 Blackhawks won the franchise's first Stanley Cup since 1961.
Campbell was a salary cap casualty in 2011 and was traded to Florida, but he returned to Chicago as a free agent before last season. He had five goals, 12 assists and was a plus-12 and then became an unrestricted free agent.
The smooth-skating, left-shooting, offensive-minded defenseman played in 423 consecutive games from 2011-16. His ironman streak ended in December not because of injury but when coach Joel Quenneville made Campbell a healthy scratch.
Information from The Associated Press was used in this report.