Crosby has recorded a point in nine straight games against the Hurricanes, and he'll hope to see the injury-riddled Penguins get some reinforcements back Friday night in Raleigh as they go for a fifth consecutive win versus Carolina.
Pittsburgh (27-11-1) had won a season-high seven in a row before Monday's 5-0 loss at Ottawa to open a four-game road trip.
"I think we knew we weren't going to win every game until the end, but every time you lose it's frustrating, especially when it's 5-0," goaltender Marc-Andre Fleury said.
That was the end of Crosby's 10-game point streak, during which he recorded seven goals and 11 assists, though that was the least of the Penguins' concerns. Crosby briefly left after a first-period collision with linemate Pascal Dupuis that he said "almost blew my knee out," but Dupuis wasn't as lucky. The winger was helped off and Pittsburgh announced Friday that he'll have ACL surgery and likely miss the rest of the season.
"There's a lot that he brings," coach Dan Bylsma told the team's official website. "He's also a big part of that dressing room. That is part of what we'll miss from Pascal."
Bylsma's club will get at least a few players back Friday. Glass and Orpik are expected to play, defenseman Deryk Engelland is available to return from a five-game suspension and Scuderi and Malkin are close to returning.
Carolina (14-15-8) certainly doesn't want the Penguins to have any additional help. Pittsburgh has won each of the past four matchups by multiple goals, outscoring the Hurricanes 21-9.
That includes two meetings this season in which Crosby had two assists apiece. He's recorded two goals and 13 assists during his nine-game series point streak.
Carolina comes back from the Christmas break hoping to again stop a brief losing streak. The Hurricanes thought they were on their way to ending a two-game skid Monday, up 3-2 on Columbus with less than five minutes remaining, but gave up two goals in 1:28 to lose 4-3 in regulation.
"It felt like we shot ourselves in the foot," captain Eric Staal said. "This was a game we had to have. You can't lose points in your own building when you're up by one with 10 minutes left. It's frustrating, and guys aren't happy about it."
Carolina has dropped six of seven and has blown leads in each of its three straight losses.
"We're not a team that's going to sit back," said Jeff Skinner, who has an NHL-high 10 goals since Dec. 3. "When we get the lead, you're not going to see us sit back. That's not our game. At the same time, we've got to make smart plays."
Skinner has failed to record a point in his last three games against the Penguins, though he missed a 3-1 home loss Oct. 28 with an upper-body injury. Staal went scoreless in that matchup after having two goals and four assists in his previous four versus Pittsburgh.
Brother Jordan has yet to score a goal in five games against his former team.
Justin Peters, who has started four of Carolina's last five games, is 2-4-1 with a 4.22 goals-against average against the Penguins.
The Hurricanes will be without Jiri Tlusty for two to three weeks after the forward underwent an emergency appendectomy Tuesday. The team filled his spot by recalling forward Zach Boychuk from Charlotte of the AHL.