Jason Spezza has scored in each of the last two games and was a big reason Ottawa won last season's series with Pittsburgh. He went pointless in the first meeting, won by the Penguins, but had four goals and four assists in the final three as the Senators won them all.
After three straight wins to open the season, the Senators open a three-game homestand with starting goalie Craig Anderson back between the pipes as they look to bounce back from their first loss.
Backup Ben Bishop, making his first start of the season, allowed five goals in a 6-4 loss at Tampa Bay on Friday.
"We're just like everyone else, we're trying to find some consistency in our game," coach Paul MacLean said.
Anderson, though, has shined with a 0.67 GAA in his three wins. He's 3-2-1 with a 2.67 GAA in seven career starts against the Penguins.
He'll have to deal with Pittsburgh star Sidney Crosby, who has started to heat up with three goals and an assist in his last two after scoring twice in a 4-2 loss at Winnipeg on Friday.
While Crosby has nine points in his last five matchups with Senators, Evgeni Malkin has 10 goals in his past 10 games against them.
The Penguins will try to get their power play hot again, having converted 1 of 6 chances in the last two games after going 4 for 8 in the first two.
That may be a difficult task against Ottawa, which has killed 15 of 18 short-handed situations.