Series: Game 3 of 3

Chi White Sox won 2-1

Game 1: Monday, May 20
Chi White Sox6
Game 2: Tuesday, May 21
Chi White Sox3
Game 3: Wednesday, May 22
Chi White Sox2

Red Sox 6

(28-19, 15-9 away)

White Sox 2

(21-24, 10-10 home)

    8:10 PM ET, May 22, 2013

    U.S. Cellular Field, Chicago, Illinois 

    123456789 R H E
    BOS 200000022 6 9 0
    CHW 001000001 2 6 0

    W: C. Buchholz (7-0)

    L: H. Santiago (1-3)

    Red Sox-White Sox Preview


    Wednesday night's game between the Chicago White Sox and visiting Boston Red Sox was scheduled to be a potential duel between two of this season's most successful starting pitchers.

    Instead, Chicago will send Hector Santiago to the mound in place of the injured Chris Sale to oppose Clay Buchholz as it goes for its first series sweep of the season.

    Sale, 4-0 with a 1.18 ERA in his last five starts, hasn't allowed a run in 23 straight innings, and his six-start streak of lasting at least seven while allowing fewer than three earned runs is the longest by a White Sox starter since Mark Buehrle's seven-start run in 2007.

    Chicago announced Tuesday, though, that the left-hander had been scratched from this start due to mild tendinitis in his shoulder.

    Santiago (1-2, 2.78 ERA) will take the hill in Sale's place. He has gone 1-1 with a 2.95 ERA in four starts since making his first May 2, but he walked four and gave up three runs in 3 1/3 innings of Chicago's 12-9 loss to the Los Angeles Angels on Saturday.

    He said he noticed his high pitch count in the fourth before being removed.

    "I'm never like that. I go inning by inning. If I go five, if I go seven, it doesn't matter," Santiago said. "(I'm) just trying to make better pitches."

    The only time Santiago, who has yet to make a start at home this season, has faced Boston was July 18, when he allowed two runs in three innings of relief in Chicago's 10-1 loss.

    He seeks a better performance this time around for the White Sox (21-23), who have won six of nine after Jose Quintana took a no-hitter into the seventh inning of Tuesday's 3-1 victory. David Ortiz's one-out single in the seventh marked the Red Sox's first hit.

    "Our starting pitching's really good," said Jeff Keppinger, who hit a two-run homer. "Every game, we're in it. It's just a matter of if we can get that big hit."

    Alex Rios went 2 for 4 with an RBI double and is batting .391 during a career-best 16-game hitting streak. Rios, though, is 2 for 13 off Buchholz, who seeks his first victory in four outings.

    Buchholz (6-0, 1.78) won his first six starts behind a 1.01 ERA, but he's posted a 3.43 ERA over his last three. He struck out nine and gave up two runs in seven innings of a 3-2, 10-inning win over Minnesota on Friday, marking the sixth time he's finished with at least eight strikeouts.

    "Team wins. That's what this game's about. There's absolutely no disappointment (not earning a decision)," said Buchholz, whose ERA is best in the AL.

    The right-hander also didn't pick up a victory despite a stellar start the last time he faced the White Sox, giving up one run in eight innings of a 3-1 win July 19. He's 1-1 with a 1.71 ERA over his last three outings against Chicago.

    The Red Sox (27-19) have dropped the first two games of this set after winning five straight. Ortiz is 1 for 7 after entering the series batting .429 during a seven-game hitting streak.

    Boston outfielder Shane Victorino didn't play Tuesday because of tightness in his left hamstring and is day to day.

    The Red Sox have lost three straight road meetings with the White Sox after winning the previous five.

    Copyright by STATS LLC and The Associated Press


    Gameday Matchup

    Current StreakL2L1
    Last 105-53-7

    Pitching Matchup

    C. Buchholz
    12-1, 1.74 ERA

    Last Game:
    9/27 at BAL
    7.0 IP, 3 ER
    Dec = Win
    H. Santiago
    4-9, 3.56 ERA

    Last Game:
    9/24 at CLE
    6.1 IP, 3 ER
    Dec = ND

    Gameday Lineups

    1. J. Ellsbury, CF A. De Aza, CF
    2. J. Gomes, LF A. Ramirez, SS
    3. D. Pedroia, 2B A. Rios, RF
    4. D. Ortiz, DH A. Dunn, DH
    5. M. Napoli, 1B P. Konerko, 1B
    6. D. Nava, RF D. Viciedo, LF
    7. W. Middlebrooks, 3B C. Gillaspie, 3B
    8. S. Drew, SS J. Keppinger, 2B
    9. J. Saltalamacchia, C T. Flowers, C