MIAMI -- Luis Valbuena wasn't going to let the game go any longer.
"Ninth inning, two outs, I tried to hit a home run," Valbuena said. "I didn't want to play extra innings."
The Marlins fell to 5-17 which matches the worst start in franchise history through 22 games according to STATS. Miami had the same record in 1995.
"Cishek made a mistake up in the zone and the guy hit it out," Marlins manager Mike Redmond said. "It just seems like that's the way it's going right now for us."
Nate Schierholtz doubled and homered for Chicago, which scored the final three runs of the game.
"It was a good win for us, a good comeback," Schierholtz said. "Valbuena had a big home run in the ninth and our starting pitching has been great, they've been keeping us close in games. We just need to score them a few runs like we did tonight and we'll come out on top."
Valbuena put the first pitch he saw from Cishek into the Marlins' bullpen in right-center field.
"He's just been good, he has four home runs and he's on pace for 30-something home runs," Cubs manager Dale Sveum said. "He's done a great job. He was a huge pick-up last year."
Marmol walked Donovan Solano to begin the bottom of the ninth and Austin Kearns lined a single to left to put Solano in scoring position with no outs. Juan Pierre's bunt was fielded cleanly by catcher Welington Castillo, who threw to third for the force out.
"It's unacceptable," Pierre said of his failed sacrifice attempt. "You have one job to do; you give yourself up and bunt the guy over. You can put this one on me."
"It was a slider," Stanton said. "You're always looking for a strike; that's the ideal thing you're supposed to do in a major league game."
Marmol has not officially been named the team's closer, which Sveum believes works in his favor.
"He pitches great when he doesn't know he's the closer," Sveum joked.
Schierholtz tied the game 3-3 in the sixth with a solo home run down off Kevin Slowey the right-field line hitting the foul pole just over the fence. It was his third home run of the season.
"I knew it was going to be close, I was just praying for it to hit that foul pole," Schierholtz said. "I hit a change-up and just kind of hooked it. I was lucky that it caught that pole."
Slowey allowed three runs and five hits in six innings. He struck out six as he threw 76 of 114 pitches for strikes.
Cubs starter Edwin Jackson allowed three runs in the first two innings before holding the Marlins scoreless for the next four frames. He struck out four and walked four.
"Everything was up, slider was up, fastball was up," Jackson said. "...I just feel like I couldn't put people away earlier in the game, but we fought back, a great team effort. These are the kinds of games we know we're capable of winning."
Pierre drove in the Marlins second run with a single to center, then stole second and third, and scored on a groundout by Giancarlo Stanton for a 3-1 lead.
Back-to-back doubles by Schierholtz and Castillo pulled the visitors within 3-2.
Valbuena had four home runs in 90 games last season. ... Jackson is 1-6 with a 6.39 ERA in nine games against Miami. ... A pair of Marlins are getting closer to making their return from shoulder injuries as SS Adeiny Hechavarria is expected to have a rehab assignment next week with Single-A Jupiter before rejoining the big league club when he is eligible to come off the disabled list on May 2 and RHP Henderson Alvarez will have a 45-pitch simulated game on Saturday and will make a rehab start with Jupiter on May 2. ... The Cubs will send RHP Scott Feldman (0-3, 4.50 ERA) to the mound Friday to oppose Marlins LHP Wade LeBlanc (0-3, 6.27 ERA).